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L2407 Sigma-Aldrich

Luzindole

≥90%

Synonym: N-Acetyl-2-benzyltryptamine, N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide

  • CAS Number 117946-91-5

  • Empirical Formula (Hill Notation) C19H20N2O

  • Molecular Weight 292.37

  •  MDL number MFCD00672498

  •  PubChem Substance ID 24896315

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
assay   ≥90%
solubility   DMSO: 5 mg/mL
storage temp.   −20°C
SMILES string   CC(=O)NCCc1c(Cc2ccccc2)[nH]c3ccccc13
InChI   1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
InChI key   WVVXBPKOIZGVNS-UHFFFAOYSA-N
Gene Information   human ... MTNR1A(4543), MTNR1B(4544)

Description

Application

Luzindole has been used as a MT1/MT2 receptor antagonist to detect the role of the melatonin receptor in neutrophil migration

Packaging

5 mg in glass bottle

Biochem/physiol Actions

Luzindole is a melatonin (mel) receptor antagonist. It has higher affinity towards the Mel 1b receptor than the Mel 1a receptor subtype.

Features and Benefits

This compound is featured on the Melatonin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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