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L3271 Sigma-Aldrich

Lys-Tyr-Lys acetate salt

≥97% (HPLC)

Synonym: Lysyltyrosyllysine, acetate

  • Empirical Formula (Hill Notation) C21H35N5O5 · xC2H4O2

  • Molecular Weight 437.53 (free base basis)

  •  MDL number MFCD00079406

  •  PubChem Substance ID 24896335

  •  NACRES NA.26

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Properties

Related Categories Biochemicals and Reagents, Dipeptides and Tripeptides, Peptides, Tripeptides
Quality Level   100
assay   ≥97% (HPLC)
form   powder
color   white to off-white
storage temp.   −20°C
SMILES string   CC(O)=O.NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O
InChI   1S/C21H35N5O5.C2H4O2/c22-11-3-1-5-16(24)19(28)26-18(13-14-7-9-15(27)10-8-14)20(29)25-17(21(30)31)6-2-4-12-23;1-2(3)4/h7-10,16-18,27H,1-6,11-13,22-24H2,(H,25,29)(H,26,28)(H,30,31);1H3,(H,3,4)/t16-,17-,18-;/m0./s1
InChI key   OXXOYNFTOCTMGG-UVJOBNTFSA-N

Description

Amino Acid Sequence

Lys-Tyr-Lys

Application

Lysyltyrosyllysine (Lys-Tyr-Lys, KYK) is used together with uracil DNA glycosylase to quantify uracil. Lysyltyrosyllysine is also used as a model peptide to study free radical oxidation and electron capture mechanisms.

Biochem/physiol Actions

Tripeptide can induce nicks at apurinic/apyrimidinic sites in circular DNA.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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