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L4897 Sigma-Aldrich

Luteinizing hormone releasing hormone salmon

≥97% (HPLC)

Synonym: GnRH, Gonadoliberin, Gonadotropin releasing hormone, LH-RH

  • CAS Number 86073-88-3

  • Empirical Formula (Hill Notation) C60H73N15O13

  • Molecular Weight 1212.31

  •  MDL number MFCD00133497

  •  PubChem Substance ID 24896381

  •  NACRES NA.32

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, LH-RH, Neuropeptides, Peptides and Proteins,
Quality Level   200
assay   ≥97% (HPLC)
storage temp.   −20°C
SMILES string   CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CO)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(Cc6cnc[nH]6)NC(=O)C7CCC(=O)N7)C(=O)N8CCCC8C(=O)NCC(N)=O
InChI   1S/C60H73N15O13/c1-32(2)20-47(60(88)75-19-7-12-49(75)59(87)65-28-50(61)78)73-55(83)44(22-34-25-63-40-10-5-3-8-38(34)40)69-52(80)29-66-53(81)43(21-33-13-15-37(77)16-14-33)70-58(86)48(30-76)74-56(84)45(23-35-26-64-41-11-6-4-9-39(35)41)71-57(85)46(24-36-27-62-31-67-36)72-54(82)42-17-18-51(79)68-42/h3-6,8-11,13-16,25-27,31-32,42-49,63-64,76-77H,7,12,17-24,28-30H2,1-2H3,(H2,61,78)(H,62,67)(H,65,87)(H,66,81)(H,68,79)(H,69,80)(H,70,86)(H,71,85)(H,72,82)(H,73,83)(H,74,84)
InChI key   NMJREATYWWNIKX-UHFFFAOYSA-N
Gene Information   human ... GNRH1(2796), GNRHR(2798)
mouse ... GNRH1(14714), GNRHR(14715)
rat ... GNRH1(25194), GNRHR(81668)

Description

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2

Application

Luteinizing hormone releasing hormone (salmon) has been used to study the effect of LHRH (luteinizing hormone releasing hormone) in the brain of Podarcis sicula sicula (male) during reproduction. It has been used to study the hormonal regulation of PACAP (pituitary adenylate cyclase-activating polypeptide) and its receptor, PAC1 (adenylate cyclase activating polypeptide 1 (pituitary) receptor type I).

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

Other Notes

Lyophilized from 0.5% acetic acid

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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