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L6882 Sigma-Aldrich

D-Luciferin sodium salt

lyophilized powder, synthetic

Synonym: (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid sodium salt, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt, Firefly luciferin sodium salt

  • CAS Number 103404-75-7

  • Empirical Formula (Hill Notation) C11H7N2NaO3S2

  • Molecular Weight 302.30

  •  MDL number MFCD00044938

  •  PubChem Substance ID 24896446

  •  NACRES NA.32

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Properties

Related Categories Analytical and Industrial Enzymes, Biochemicals and Reagents, Chemiluminescent compounds, Core Bioreagents, Enzyme Substrates,
Quality Level   200
biological source   synthetic
assay   ≥98% (HPLC)
form   lyophilized powder
solubility   H2O: soluble
fluorescence   λex 328 nm; λem 532 nm in H2O
storage temp.   −20°C
SMILES string   [Na+].Oc1ccc2nc(sc2c1)C3=N[C@H](CS3)C([O-])=O
InChI   1S/C11H8N2O3S2.Na/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;/h1-3,7,14H,4H2,(H,15,16);/q;+1/p-1/t7-;/m1./s1
InChI key   LILQLBIQROYWIA-OGFXRTJISA-M

Description

General description

D-Luciferin is mainly produced in bioluminescent organisms. It can simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. D-Luciferin is also sensitive to moisture in its powder form.

Application

D-Luciferin sodium salt has been used as a substrate in luciferin−luciferase chemiluminescence assay to determine ATP levels.

Substrate for firefly luciferase with a Km of approx 2 μM.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

HPLC Analysis of Luciferin Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Luciferin Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Luciferin Enantiomers on CHIRALPAK® AGP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Luciferin Enantiomers on CHIRALPAK® AGP
Keywords: Chromatography, High performance liquid chromatography, Vitamins

Peer-Reviewed Papers
15

References

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