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L6895 Sigma-Aldrich

Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 (Re mutant)

lyophilized powder, TLR ligand tested




Lipid A molecules compose the lipid membrane anchoring core components of endotoxins produced by Gram-negative bacteria. Lipid A molecules induce immune responses. Structually, lipid A molecules are composed of two glucosamine units with varied, species dependent, fatty acyl chain numbers and identity and degree of phosphorylation.
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.


1, 5 mg in glass bottle

Biochem/physiol Actions

Lipid A has immunostimulatory adjuvant activity including macrophage, T-cell, and B-cell activation. Research has shown Lipid A has greater Th1 than Th2 stimulation.

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND

Pipette Controller from Brand
Protocols & Articles


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