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L8912 Sigma-Aldrich

L-Leucine

from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Synonym: (S)-2-Amino-4-methylpentanoic acid

  • CAS Number 61-90-5

  • Linear Formula (CH3)2CHCH2CH(NH2)CO2H

  • Molecular Weight 131.17

  •  Beilstein/REAXYS Number 1721722

  •  EC Number 200-522-0

  •  MDL number MFCD00002617

  •  eCl@ss 32160406

  •  PubChem Substance ID 24896510

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Amino Acids & Derivatives, Amino Acids & Vitamins, Amino Acids and Vitamins, Amino acids,
Quality Level   PREMIUM
biological source   non-animal source
InChI Key   ROHFNLRQFUQHCH-YFKPBYRVSA-N
assay   98.5-101.0%
form   powder
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
mp   >300 °C (lit.)
solubility   1 M HCl: 50 mg/mL
suitability   meets EP, JP, USP testing specifications
Featured Industry   Pharmaceutical (small molecule)

Description

Application

L-leucine has been used as a hypertrophic agent to monitor its effects on myotubes. It has also been used as a component of PMG media for culturing yeast.

Packaging

1 kg in poly bottle

10 mg in glass bottle

25, 100 g in poly bottle

Biochem/physiol Actions

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
OH2850000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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