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L9037 Sigma-Aldrich

L-Lysine monohydrate

BioReagent, suitable for cell culture, from non-animal source

  • CAS Number 39665-12-8

  • Empirical Formula (Hill Notation) C6H14N2O2 · H2O

  • Molecular Weight 164.20

  •  Beilstein/REAXYS Number 4349963

  •  EC Number 200-294-2

  •  MDL number MFCD00151035

  •  PubChem Substance ID 24896515

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Properties

Related Categories Amino Acids & Vitamins, Amino acids, Cell Biology, Core Bioreagents, Functional Foods,
Quality Level   200
biological source   non-animal source
product line   BioReagent
assay   98.5-101.5% dry basis
form   crystalline powder
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
color   white
mp   215 °C
solubility   H2O: soluble
SMILES string   [H]O[H].NCCCC[C@H](N)C(O)=O
InChI   1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1
InChI key   HZRUTVAFDWTKGD-JEDNCBNOSA-N

Description

General description

L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.

Application

L-Lysine monohydrate has been used in:
• SILAC (stable isotope labeling by amino acids in cell culture) method
• the complete synthetic (C) medium for positive selection screening of yeast cells
• the growth medium for cells

Packaging

1 kg in poly bottle

25, 100 g in poly bottle

Biochem/physiol Actions

L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers, and a substrate for oxidation and glycation mechanism studies.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
OL5540000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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