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L9045 Sigma-Aldrich

Lipodisq®

Styrene:Maleic Anhydride Copolymer 3:1

  •  NACRES NA.26

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Properties

Related Categories Biochemicals and Reagents, Biodegradable Polymers, Lipodisq, Lipodisq Reagents, Materials Science,
Quality Level   200
biological source   synthetic
form   powder
storage temp.   room temp

Description

General description

Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq® polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.

Packaging

100 mg in poly bottle

Application

Lipodisq reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.

The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.

Functional pH range: 6.0 - 9.0

Biochem/physiol Actions

Lipodisq® polymers are potentially useful in mitigating the use of detergents for solubilization of membrane proteins. Dissolving this product in an aqueous solution, with sufficient base (e.g. KOH, NaOH), causes hydrolysis of each anhydride moiety into two carboxylic acid/carboxylate groups. This action renders the SMA polymer soluble in aqueous media. Lipodisq® acts as a potential membrane mimic system.

Legal Information

Lipodisq is a registered trademark of Malvern Cosmeceutics Limited

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Biomaterials Tutorial

Biocompatible Polymers Biodegradable Polymers Crosslinkers Biocompatible Inorganic Materials Supramolecular Chemistry
Keywords: Agriculture, Antimicrobials, Biomaterials, Ceramics, Chromatography, Cosmetics, Degradations, Diffusion, Environmental, Genomics, Germination, Nanomaterials, Oxidations, Petrochemical, Pharmaceutical, Polymerization reactions, Proteomics, Reductions

Peer-Reviewed Papers
15

References

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Description

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L9170 Lipodisq®, Styrene:Maleic Anhydride Copolymer 3:1, Pre-hydrolyzed

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