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L9750 Sigma-Aldrich

Leu-Gly-Gly

Synonym: L-Leucyl-glycyl-glycine, L-leucylglycylglycine

  • CAS Number 1187-50-4

  • Linear Formula (CH3)2CHCH2CH(NH2)CONHCH2CONHCH2COOH

  • Molecular Weight 245.28

  •  Beilstein/REAXYS Number 1728928

  •  EC Number 214-698-1

  •  MDL number MFCD00065942

  •  PubChem Substance ID 24896460

  •  NACRES NA.26

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Properties

Related Categories Biochemicals and Reagents, Dipeptides and Tripeptides, Peptides, Tripeptides
Quality Level   200
assay   ≥98% (TLC)
form   powder
application(s)   ligand binding assay: suitable
color   white to off-white
storage temp.   −20°C
SMILES string   CC(C)C[C@H](N)C(=O)NCC(=O)NCC(O)=O
InChI   1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
InChI key   VWHGTYCRDRBSFI-ZETCQYMHSA-N
Gene Information   human ... SLC15A1(6564)

Description

Amino Acid Sequence

Leu-Gly-Gly

Biochem/physiol Actions

Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidase (EC 3.4.11.4) and other peptidase(s) such as leucylglycylglycine aminopeptidase (EC 3.4.1.3).

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L9750.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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