LO1280 Sigma-Aldrich


Synonym: Library of Pharmacologically Active Compounds



Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Culture, Compound Libraries,
Quality Level   100
shipped in   dry ice
storage temp.   −20°C


General description

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).


LOPAC®1280 has been used:
• in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
• to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
• in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
• in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein

Features and Benefits

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

• Apoptosis
• G Proteins & Cyclic Nucleotides
• Gene Regulation & Expression
• Ion Channels
• Lipid Signaling
• Multi-Drug Resistance
• Neurotransmission
• Phosphorylation

SDFile provided to construct a database containing:
• Structure
• Primary Name
• Secondary Name
• Pharmacological Activity
• Product Number
• Rack Position

Collection of 1,280 Pharmacologically-Active Sigma Compounds

To request a list of components, please visit

Other Notes

For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

NA 1993 / PGIII
WGK Germany 
Flash Point(F) 
188.6 °F - closed cup
Flash Point(C) 
87 °C - closed cup
Protocols & Articles

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