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M006 Sigma-Aldrich

Proglumide sodium salt

solid

Synonym: 4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid sodium-potassium salt, N-Benzoyl-N′,N′-dipropyl-DL-isoglutamine sodium-potassium salt

  • CAS Number 99247-33-3

  • Empirical Formula (Hill Notation) C18H25N2NaO4

  • Molecular Weight 356.39

  •  MDL number MFCD00069301

  •  PubChem Substance ID 24896533

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholecystokinins, Cholecystokinnin - Receptor Antagonists,
Quality Level   100
form   solid
color   white
solubility   H2O: soluble
SMILES string   [Na+].CCCN(CCC)C(=O)C(CCC([O-])=O)NC(=O)c1ccccc1
InChI   1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1
InChI key   UFMWGCINVOIJSO-UHFFFAOYSA-M
Gene Information   human ... CCK(885), CCKAR(886), CCKBR(887)
mouse ... CCK(12424)
rat ... CCK(25298)

Description

Application

Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.

Packaging

100, 500 mg in poly bottle

Biochem/physiol Actions

Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.

CCK antagonist; selectively blocks CNS effects.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Proglumide Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proglumide Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Proglumide Enantiomers on Astec® Cellulose DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proglumide Enantiomers on Astec® Cellulose DMP
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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