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M0443 Sigma-Aldrich

Mirtazapine

≥98% (HPLC)

Synonym: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine

  • CAS Number 85650-52-8

  • Empirical Formula (Hill Notation) C17H19N3

  • Molecular Weight 265.35

  •  MDL number MFCD00865427

  •  PubChem Substance ID 24724531

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white
solubility   DMSO: 8 mg/mL, clear
SMILES string   CN1CCN2C(C1)c3ccccc3Cc4cccnc24
InChI   1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
InChI key   RONZAEMNMFQXRA-UHFFFAOYSA-N
Gene Information   human ... ADRA2A(150), ADRA2B(151), ADRA2C(152), DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HTR1A(3350), HTR2A(3356), HTR2C(3358), HTR7(3363)
mouse ... Slc6a2(20538)
rat ... Adra1a(29412), Drd1a(24316), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr2c(25187), Slc6a3(24898), Slc6a4(25553)

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M0443.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Central nervous system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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