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M1380 Sigma-Aldrich

N6-Monobutyryladenosine 3′:5′-cyclic monophosphate sodium salt

Synonym: 6MB-cAMP

  • CAS Number 70253-67-7

  • Empirical Formula (Hill Notation) C14H17N5NaO7P

  • Molecular Weight 421.28

  •  MDL number MFCD00057135

  •  PubChem Substance ID 24896638

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotide Analogs More...
Quality Level   100
biological source   synthetic (organic)
assay   ≥97.5% (HPLC)
form   powder or crystals
solubility   water: 50 mg/mL, clear, colorless
storage temp.   −20°C
SMILES string   [Na].CCCC(=O)Nc1ncnc2n(cnc12)C3OC4COP(O)(=O)OC4C3O
InChI   1S/C14H18N5O7P.Na.H/c1-2-3-8(20)18-12-9-13(16-5-15-12)19(6-17-9)14-10(21)11-7(25-14)4-24-27(22,23)26-11;;/h5-7,10-11,14,21H,2-4H2,1H3,(H,22,23)(H,15,16,18,20);;
InChI key   RHNOUOJKQVKESB-UHFFFAOYSA-N

Description

Application

N6-Monobutyryladenosine 3′:5′-cyclic monophosphate sodium salt is suitable:
• to test the hypothesis that it stimulates the long-lasting potentiation of post ganglionic response
• as protein kinase A activator, in human primary cultured thyrocytes for analyzing the modulations in cAMP cascade regulated gene expression
• to analyse its effect on progesterone production in corpus luteum isolated from pseudopregnant rabbits

Biochem/physiol Actions

Membrane permeable analog of cAMP that activates protein kinase A and is resistant to degradation by phosphodiesterase

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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