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M2028 Sigma

Capsaicin

≥95%, from Capsicum sp.

Synonym: 8-Methyl-N-vanillyl-trans-6-nonenamide

  • CAS Number 404-86-4

  • Linear Formula (CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)

  • Molecular Weight 305.41

  •  Beilstein Registry Number 2816484

  •  EC Number 206-969-8

  •  MDL number MFCD00017259

  •  PubChem Substance ID 24896598

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Properties

Related Categories Alkaloid, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology,
biological source   Capsicum sp.
InChI Key   YKPUWZUDDOIDPM-SOFGYWHQSA-N
assay   ≥95%
mp   62-65 °C (lit.)
solubility   H2O: insoluble
  ethanol: soluble
storage temp.   2-8°C
Gene Information   human ... CYP1A2(1544), TRPV1(7442)
rat ... Trpv1(83810), Trpv4(66026)

Description

Packaging

1 g in glass bottle

250 mg in glass bottle

50 mg in poly bottle

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1544PSN1 6.1 / PGIII
WGK Germany 
3
RTECS 
RA8530000
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Peer-Reviewed Papers
15

References

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