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M6020 Sigma-Aldrich

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

Synonym: D-Mannopyranose

  • CAS Number 3458-28-4

  • Empirical Formula (Hill Notation) C6H12O6

  • Molecular Weight 180.16

  •  Beilstein/REAXYS Number 1564373

  •  EC Number 222-392-4

  •  MDL number MFCD00064122

  •  PubChem Substance ID 24897068

  •  NACRES NA.75

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Properties

Related Categories Carbohydrates, Cell Biology, Cell Culture, Functional Foods, Miscellaneous Reagents and Supplements,
Quality Level   200
biological source   plant (Spruce, Birch or Beech Wood, Glucose)
product line   BioReagent
assay   ≥99%
form   powder
application(s)   cell culture | mammalian: suitable
mp   133-140 °C (lit.)
solubility   H2O: 50 mg/mL
Featured Industry   Agriculture
SMILES string   OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
InChI   1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
InChI key   WQZGKKKJIJFFOK-QTVWNMPRSA-N

Description

General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration. Majority of mannose is synthesised from its epimer glucose. It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.

Application

D-(+)-Mannose has been used:
•  as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
•  as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
• in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines

Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

Packaging

25, 100, 500 g in poly bottle

Biochem/physiol Actions

Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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