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M6514 Sigma-Aldrich

3-(Trimethoxysilyl)propyl methacrylate

≥97%

Synonym: Silane A174, [3-(Methacryloyloxy)propyl]trimethoxysilane

  • CAS Number 2530-85-0

  • Linear Formula H2C=C(CH3)CO2(CH2)3Si(OCH3)3

  • Molecular Weight 248.35

  •  Beilstein/REAXYS Number 1952435

  •  EC Number 219-785-8

  •  MDL number MFCD00008593

  •  PubChem Substance ID 24897091

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Properties

Related Categories Chemical Synthesis, Organometallic Reagents, Organosilicon, Trialkoxysilanes
Quality Level   100
assay   ≥97%
form   liquid
refractive index   n20/D 1.431 (lit.)
bp   190 °C (lit.)
density   1.045 g/mL at 25 °C (lit.)
storage temp.   2-8°C
SMILES string   CO[Si](CCCOC(=O)C(C)=C)(OC)OC
InChI   1S/C10H20O5Si/c1-9(2)10(11)15-7-6-8-16(12-3,13-4)14-5/h1,6-8H2,2-5H3
InChI key   XDLMVUHYZWKMMD-UHFFFAOYSA-N

Description

General description

3-(Trimethoxysilyl)propyl methacrylate (TMSPMA) is a hydrophobic monomer. The presence of an additional functional group of acrylate facilitates TMSPMA for grafting polymerization on plastic surfaces. 3-(Trimethoxysilyl)propyl methacrylate undergoes first-order kinetic polymerization to form polyTMSPMA, which is a moisture stable polymer.

Application

3-(Trimethoxysilyl)propyl methacrylate has been used in the following applications:
• Isoelectric focusing can lead to pH gradient formation resulting in the swelling or shrinking of gel casts. This can be prevented by using 3-(Trimethoxysilyl)propyl methacrylate to link polyacrylamide gels to glass plates covalently.
• In situ hybridization using 3-(Trimethoxysilyl)propyl methacrylate along with poly-L-lysine is a faster and durable method to attach cells, microscopic sections, and total organs to slides/other glass surfaces.
• 3-(Trimethoxysilyl)propyl methacrylate is also used in the preparation of organic/inorganic hybrid nanomaterials.

Packaging

25, 50 mL in glass bottle

A product Information sheet is supplied which describes procedures for using this product.

Safety & Documentation

Safety Information

RIDADR 
NA 1993 / PGIII
WGK Germany 
WGK 1
Protocols & Articles
Peer-Reviewed Papers
15

References

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