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M6949 Sigma-Aldrich

Madecassoside from Centella asiatica

≥95% (HPLC)

Synonym: Asiaticoside A, Madecassoside, Redermic

  • CAS Number 34540-22-2

  • Empirical Formula (Hill Notation) C48H78O20

  • Molecular Weight 975.12

  •  EC Number 252-076-1

  •  NACRES NA.25

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Properties

Related Categories Cell Biology, Nutrition Research, Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM) More...
Quality Level   200
assay   ≥95% (HPLC)
form   powder
color   white to off-white
solubility   H2O: 1 mg/mL, clear, colorless
storage temp.   2-8°C
InChI   1S/C48H78O20/c1-19-10-11-48(13-12-46(6)22(28(48)20(19)2)8-9-27-44(4)14-24(52)39(61)45(5,18-50)38(44)23(51)15-47(27,46)7)43(62)68-42-35(59)32(56)30(54)26(66-42)17-63-40-36(60)33(57)37(25(16-49)65-40)67-41-34(58)31(55)29(53)21(3)64-41/h8,19-21,23-42,49-61H,9-18H2,1-7H3
InChI key   BNMGUJRJUUDLHW-UHFFFAOYSA-N

Description

Packaging

10 mg in glass bottle

50 mg in poly bottle

Biochem/physiol Actions

Madecassoside is a triterpenoid compound found in Centella asiatica (Gotu kola), a medicinal herb used in traditional Chinese medicine (TCM), Ayurvedic medicine, and traditional African medicine. Madecassoside has a wide range of reported biological activities including, anti-inflammatory, wound healing, and anti-oxidant activities. It has been reported to suppress LPS-induced TNF-alpha production via inhibition of ERK, p38, and NF-kappaB activity.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
YU9555000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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