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M7441 Sigma-Aldrich

Monoamine Oxidase B human

recombinant, expressed in baculovirus infected BTI insect cells

Synonym: MAO-B

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Description

Biochem/physiol Actions

MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

General description

Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.

Application

Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression.

Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Metabolomics, Molecular biology

Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

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M7566 Monoamine Oxidase Insect Cell Control, recombinant, expressed in wild-type baculovirus infected BTI insect cells
M7316 Monoamine Oxidase A human, recombinant, expressed in baculovirus infected BTI insect cells
M1821 Anti-Monoamine Oxidase B antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution
M1946 Anti-Monoamine Oxidase B (C-terminal) antibody produced in rabbit, affinity isolated antibody, ~1.5 mg/mL, buffered aqueous solution

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