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M8439 SAFC

L-Methionine

PharmaGrade, Ajinomoto, EP, JP, USP, manufactured under appropriate GMP controls for Pharma or Biopharmaceutical production, suitable for cell culture

Synonym: (S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

  • CAS Number 63-68-3

  • Linear Formula CH3SCH2CH2CH(NH2)CO2H

  • Molecular Weight 149.21

  •  Beilstein/REAXYS Number 1722294

  •  EC Number 200-562-9

  •  MDL number MFCD00063097

  •  eCl@ss 32160406

  •  PubChem Substance ID 57654418

  •  NACRES NA.26

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Properties

Related Categories Amino Acids, Amino acids, Analytical/Chromatography, Biochemicals and Reagents, Cell Biology,
biological source   non-animal source
Agency/Method   EP
  JP
  USP
product line   PharmaGrade
assay   ≥99%
form   powder
mfr. no.   Ajinomoto
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, heavy metals, trace metals, residual solvents, tested
mp   284 °C (dec.) (lit.)
solubility   H2O: 50 mg/mL
suitability   suitable for manufacturing use
Featured Industry   Pharmaceutical (small molecule)
foreign activity   cytotoxicity, tested
SMILES string   CSCC[C@H](N)C(O)=O
InChI   1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChI key   FFEARJCKVFRZRR-BYPYZUCNSA-N
Gene Information   rat ... Ggt1(116568)

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.
To request the Enhanced Quality Product Documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Application

L-Methionine is an essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

HPLC Analysis of t-BOC-Methionine Enantiomers on Astec® (R,R) P-CAP™

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of t-BOC-Methionine Enantiomers on Astec® (R,R) P-CAP™
Keywords: Chromatography, High performance liquid chromatography

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

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Peer-Reviewed Papers
15

References

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