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M8693 Sigma-Aldrich

Melanotan II acetate salt

≥95% (HPLC)

Synonym: Ac-[Nle4Asp5D-Phe7Lys10]α-MSH-(4-10)-NH2

  • CAS Number 121062-08-6 (free base)

  • Empirical Formula (Hill Notation) C50H69N15O9 · xC2H4O2

  • Molecular Weight 1024.18 (free base basis)

  •  MDL number MFCD06795842

  •  NACRES NA.32

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Melanocyte Stimulating Hormone (MSH),
Quality Level   200
assay   ≥95% (HPLC)
form   lyophilized solid
color   white
solubility   H2O: soluble 5 mg/mL
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... MC3R(4159), MC4R(4160)
mouse ... MC3R(17201), MC4R(17202)
rat ... MC3R(29310), MC4R(25635)

Description

Amino Acid Sequence

Ac-Nle-Asp-His-Phe-Arg-Trp-Lys-NH2

General description

Melanotan II induces melanogenesis and thus increases skin pigmentation. It is an analog of α-melanocyte stimulating hormone.

Application

Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Melanotan II is a MC3-R/MC4-R melanocortin agonist.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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