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M9656 Sigma-Aldrich

H-8 dihydrochloride

>98% (HPLC)

Synonym: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide hydrochloride

  • CAS Number 113276-94-1

  • Empirical Formula (Hill Notation) C12H15N3O2S · 2HCl

  • Molecular Weight 338.25

  •  MDL number MFCD00036962

  •  PubChem Substance ID 24278039

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
assay   >98% (HPLC)
storage temp.   2-8°C
SMILES string   Cl[H].Cl[H].CNCCNS(=O)(=O)c1cccc2cnccc12
InChI   1S/C12H15N3O2S.2ClH/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12;;/h2-6,9,13,15H,7-8H2,1H3;2*1H
InChI key   RJJLZYZEVNCZIW-UHFFFAOYSA-N
Gene Information   human ... CALCRL(10203), PRKAR1A(5573), PRKAR1AP(5574), PRKAR1B(5575), PRKAR2A(5576), PRKAR2B(5577)
rat ... Calcrl(25029)

Description

Packaging

5 mg in glass bottle

Biochem/physiol Actions

cAMP and cGMP-dependent protein kinase inhibitor.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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