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MI00100 Sigma-Aldrich

MISSION® microRNA Mimic

Human Library

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Properties

Related Categories Functional Genomics and RNAi, Molecular Biology, miRNA, miRNA mimic library
product line   MISSION®
storage temp.   −20°C

Description

General description

Human miRNA mimic library, based on miRBase Version 13 from the Sanger Institute, supplied as 985 mimics at 0.25nmol each in 96 well plate format.

The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute).

• Optimized and ready for transfection.
• Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets.
• Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects.
• Available as a whole human library and individual miRNA targets.

Legal Information

MISSION is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

RNAi Tools for Epigenetics Research

RNA interference (RNAi) is a relatively new technology that is revolutionizing the way researchers study gene expression. RNAi is a highly conserved gene silencing mechanism that occurs in response t...
Savita Bagga, PhD.
BioFiles v7 n3, 2012, 17–18
Keywords: Cancer, Cell culture, Cell division, Epigenetics, Gene expression

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