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N3889 Sigma-Aldrich

Nitrazepam

  • CAS Number 146-22-5

  • Empirical Formula (Hill Notation) C15H11N3O3

  • Molecular Weight 281.27

  •  EC Number 205-665-2

  •  MDL number MFCD00058577

  •  PubChem Substance ID 24897666

  •  NACRES NA.77

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Properties

Related Categories Benzodiazepines and Anxiolytics, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
drug control   USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
SMILES string   [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3)c2c1
InChI   1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)
InChI key   KJONHKAYOJNZEC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Hypnotic; ligand for the GABAA receptor benzodiazepine modulatory site.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
DF2450000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anxiolytic Drugs on SUPELCOSIL™ LC-8
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Benzodiazepines on Ascentis® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Benzodiazepines on Ascentis® C8
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

HPLC Analysis of Nitrazepam Anticonvulsant Drugs on Ascentis® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nitrazepam Anticonvulsant Drugs on Ascentis® C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical

RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents RP-HPLC Analysis of Benzodiazepines on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of Benzodiazepines and Glucuronide Metabolites in Urine on Titan™ C18 after SPE using Supel™-Select HLB, β-Glucuronidase Enzyme Digestion
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Mass spectrometry, Metabolites, Pharmaceutical, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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