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N4256 Sigma-Aldrich

Nicotinic acid adenine dinucleotide sodium salt

≥98%

Synonym: Deamido NAD, NAAD, Nicotinic acid NAD

  • CAS Number 104809-30-5

  • Empirical Formula (Hill Notation) C21H26N6O15P2

  • Molecular Weight 664.41

  •  MDL number MFCD00082430

  •  PubChem Substance ID 24897698

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Oxidation-Reduction
InChI Key   JSOFOHZYBCRUNK-UHFFFAOYSA-N
assay   ≥98%
storage temp.   −20°C

Description

General description

Nicotinic acid adenine dinucleotide (deamido-NAD, NAAD) is a closely related analog of NAD+. It is used to study the structure of nicotinate mononucleotide adenylyltransferase(s) (NMN/NaMN). NAAD is used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS). In addition, it is also used as a co-substrate to study mechanisms of members of the Sir2 class of NAD+-dependent deacetylase.

Application

Nicotinic acid adenine dinucleotide sodium salt has been used as an internal standard during high performance liquid chromatography (HPLC) metabolite measurement. It has also been used as a substrate in nicotinamide adenine dinucleotide (NAD) biosynthesis.

Packaging

25, 100 mg in poly bottle

Other Notes

Analog of β-NAD

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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