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N4396 Sigma-Aldrich

Nalbuphine hydrochloride hydrate

≥98% (HPLC)

Synonym: 17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride hydrate

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Properties

Related Categories Abbott, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
assay   ≥98% (HPLC)
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
solubility   H2O: soluble
  ethanol: soluble
originator   Abbott
storage temp.   room temp
SMILES string   Cl[H].[H]O[H].[H][C@@]12Oc3c(O)ccc4C[C@H]5N(CC[C@@]1(c34)[C@@]5(O)CC[C@@H]2O)CC6CCC6
InChI   1S/C21H27NO4.ClH.H2O/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H;1H2/t15-,16+,19-,20-,21+;;/m0../s1
InChI key   IUGXDRGXUYNFHK-XSFMULHUSA-N
Gene Information   human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)

Description

General description

Nalbuphine functions as an analgesic. It has anti catabolic properties. Nalbuphine maybe associated with sedation, nausea and vomiting.

Packaging

25, 100 mg in glass bottle

Biochem/physiol Actions

Partial agonist for μ and κ opioid receptors.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
WGK 3
RTECS 
QD3181000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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