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  • N8658 - Monoclonal Anti-Nicotinic Acetylcholine Receptor (γ-ε Subunit) antibody produced in rat

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N8658 Sigma

Monoclonal Anti-Nicotinic Acetylcholine Receptor (γ-ε Subunit) antibody produced in rat

~5 mg/mL, clone mAb 168, purified immunoglobulin, buffered aqueous solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neurotransmission, Antibodies to Ion Channels,
species reactivity   Xenopus, mammals, Torpedo, bovine
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  western blot: suitable
clone   mAb 168, monoclonal
concentration   ~5 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CHRNE(1145), CHRNG(1146)
biological source   rat
conjugate   unconjugated

Description

Immunogen

nicotinic acetylcholine receptors from the electric eel Torpedo.

Physical form

Solution in 10 mM phosphate buffered saline, pH 7.4, containing 10 mM sodium azide.

Specificity

Recognizes γ subunits of Torpedo electric organ acetylcholine receptors and cross-reacts with ε subunits of mammalian muscle acetylcholine receptors at an epitope within amino acids 364-374. Binds well with native and denatured Torpedo acetylcholine receptors and, with lower affinity, with mammalian muscle acetylcholine receptors.

Legal Information

Sold with the permission of the Salk Institute

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WGK Germany  3
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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
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