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O0886 Sigma-Aldrich

Olomoucine

≥98% (HPLC)

Synonym: 2-(Hydroxyethylamino)-6-benzylamino-9-methylpurine

  • CAS Number 101622-51-9

  • Empirical Formula (Hill Notation) C15H18N6O

  • Molecular Weight 298.34

  •  MDL number MFCD00189360

  •  PubChem Substance ID 24278053

  •  NACRES NA.77

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Properties

Related Categories A to C, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
solubility   DMSO: 20 mg/mL, clear, colorless
storage temp.   −20°C
SMILES string   Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12
InChI   1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20)
InChI key   GTVPOLSIJWJJNY-UHFFFAOYSA-N
Gene Information   human ... CDC2(983), CDK2(1017), CDK3(1018), CDK4(1019), CDK5(1020), CDK6(1021), CDK7(1022), CDK8(1024), CDK9(1025), CDKN1A(1026), CDKN1B(1027), CDKN1C(1028), CDKN2A(1029), CDKN2B(1030), CDKN2C(1031), CDKN2D(1032), CDKN3(1033)
rat ... Prkca(24680)

Description

Biochem/physiol Actions

Olomoucine is a purine derivative which inhibits cyclin-dependent kinases and induces G arrest.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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