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O4126 Sigma

Oxaloacetic acid

≥97% (HPLC)

Synonym: 2-Oxosuccinic acid, Ketosuccinic acid, Oxalacetic acid, Oxobutanedioic acid

  • CAS Number 328-42-7

  • Linear Formula HOOCCH2COCOOH

  • Molecular Weight 132.07

  •  Beilstein Registry Number 1705475

  •  EC Number 206-329-8

  •  MDL number MFCD00002592

  •  PubChem Substance ID 24897993

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Description

Biochem/physiol Actions

Oxaloacetic acid is an intermediate in the TCA Cycle.

Packaging

1, 5, 25, 100 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Stabilizer Protein and RNA Stabilization Reagents
Protocols & Articles

Articles

Citric Acid Cycle, TCA or Krebs Cycle

Acetyl-CoA enters a cycle whose discovery by Hans Krebs 70 years ago marked a milestone in biochemistry. The citric acid cycle is also termed the tricarboxylic acid cycle, TCA cycle or Krebs cycle (s...
BioFiles 2007, 2.6, 16.
Keywords: Addition reactions, Biochemistry, Catalysis, Citric Acid Cycle, Decarboxylations, Dehydration reaction, Hydration reaction, Metabolites, Oxidations, Phosphorylations

Fatty Acid Synthesis and Metabolism in Cancer Cells

Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Biofiles, Cancer, Carboxylations, Catalysis, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations

Glutamine Metabolism is Dysregulated in Many Cancer Cells

Proliferatively active cells require both a source of carbon and of nitrogen for the synthesis of macromolecules. Although a large proportion of tumor cells utilize aerobic glycolysis and shunt metab...
Keywords: Aerobic, Biofiles, Cancer, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Metabolites, PAGE, Phosphorylations, Support, Transcription

Monosaccharide Biosynthesis

Each of the monosaccharides has its own interesting metabolism. The pathway by which a monosaccharide is made, is not the reverse of its degradation pathway (see Figure 4).
BioFiles 2007, 2.6, 21.
Keywords: Addition reactions, Biofiles, Carboxylations, Catalysis, Condensations, Decarboxylations, Degradations, Metabolic Pathways, Metabolism, Metabolites, Phosphorylations, Reductions

Protocols

Enzymatic Assay of Malic Dehydrogenase (EC 1.1.1.37)

The continuous spectrophotometric rate determination (A340, Light path = 1 cm) is based on the following reaction:
Keywords: Extinction coefficient

Peer-Reviewed Papers
15

References

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