• USA Home
  • O6503 - L-Ornithine monohydrochloride

EMAIL THIS PAGE TO A FRIEND
O6503 Sigma-Aldrich

L-Ornithine monohydrochloride

BioReagent, suitable for cell culture, ≥99%

Synonym: (S)-2,5-Diaminopentanoic acid monohydrochloride

  • CAS Number 3184-13-2

  • Empirical Formula (Hill Notation) C5H12N2O2 · HCl

  • Molecular Weight 168.62

  •  Beilstein/REAXYS Number 3625847

  •  EC Number 221-678-6

  •  MDL number MFCD00064562

  •  PubChem Substance ID 24898036

  •  NACRES NA.75

Purchase

Properties

Related Categories Allium sativum (Garlic), Amino Acids, Amino Acids and Vitamins, Amino acids, Cell Biology,
Quality Level   200
biological source   microbial
product line   BioReagent
assay   ≥99%
form   powder
packaging   pkg of 100 g
  pkg of 25 g
application(s)   cell culture | mammalian: suitable
impurities   ammonia and citrulline, essentially free
solubility   H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow
SMILES string   Cl.NCCC[C@H](N)C(O)=O
InChI   1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
InChI key   GGTYBZJRPHEQDG-WCCKRBBISA-N

Description

General description

L-Ornithine is the functional metabolite of L-arginine.

L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.

Application

L-Ornithine monohydrochloride has been used:
• as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays
• as a component in the standard medium for primary human hepatocytes (PHH) culture
• as a creatine synthesis inhibitor

Packaging

25, 100 g in poly bottle

Biochem/physiol Actions

L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.

L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.

Other Notes

Product of arginine degradation by arginase

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Request a Serum Sample
Protocols & Articles

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?