P0083 Sigma-Aldrich

PRMT1 from rat

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous solution

Synonym: HMT1-like 2, HRMT1L2, Heterogenious nuclear ribonucleoprotein methyltransferase 1-like 2, IR1B4, Interferon receptor 1-bound protein 4, Protein arginine N-methyl transferase 1

  •  NACRES NA.32



Related Categories Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators, Gene Regulation and Expression
Quality Level   200
recombinant   expressed in E. coli
assay   ≥90% (SDS-PAGE)
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   rat ... Prmt1(60421)


Biochem/physiol Actions

Methyl transferases catalyze the addition of methyl groups to nitrogen, carbon, sulfur, and oxygen atoms of small molecules, lipids, proteins, and nucleic acids. Eight mammalian protein arginine methyltransferases (PRMT) have been identified. PRMT1 is the predominant member of the methyl transferases, which catalyzes the protein arginine N-methylation reactions. PRMT1 is implicated in various cellular processes including: transcription, RNA processing, and signal transduction.

Unit Definition

The specific activity is ≥ 0.1 nmol/mgP/min. measured by 3H-AdoMet incorporation into histone for 30 minues at 30 °C.

Physical form

Solution of 50 mM Tris, pH 7.6, 5 mM DTT, 0.2% IGEPAL® CA-630, 150 mM NaCl, and 30% glycerol (w/v).

Analysis Note

The N-methyltransferase activity is determined by detecting the level of radiolabel transfer from 3H-AdoMet (Methyl donor) to histone (Cat. No. H4380), which is arginine rich (methyl acceptor).

Legal Information

IGEPAL is a registered trademark of Solvay

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

P1620 Anti-PRMT1 antibody, Mouse monoclonal, clone PRMT1-171, purified from hybridoma cell culture
P6996 Anti-PRMT1 (TK-16) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
P6871 Anti-PRMT1 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?