EMAIL THIS PAGE TO A FRIEND
P0878 Sigma-Aldrich

O-Phospho-L-serine

Synonym: L-2-Amino-3-hydroxypropanoic acid 3-phosphate, L-SOP, L-Serine O-phosphate

  • CAS Number 407-41-0

  • Linear Formula (HO)2P(O)OCH2CH(NH2)CO2H

  • Molecular Weight 185.07

  •  Beilstein/REAXYS Number 1726826

  •  EC Number 206-986-0

  •  MDL number MFCD00065935

  •  eCl@ss 32160406

  •  PubChem Substance ID 24277998

Purchase

Description

Application

O-Phospho-L-serine has been used:
• for the expression, purification and phosphorylation of protein
• to study its chemical shift
• to spectroscopically determine its pKa values using Raman spectroscopy

Packaging

10 mg in autosample vial

Biochem/physiol Actions

O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis.

Group III metabotropic glutamate receptor agonist (mGluR4, mGluR7, and mGluR8).

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
1

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Certificate of Origin

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?