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P220 Sigma-Aldrich

Peptide YY Fragment 3-36 human

≥95% (HPLC), lyophilized powder

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neuropeptide Y and Peptide YY, Neuropeptide Y and Peptide YY Peptides, Neuropeptides,
assay   ≥95% (HPLC)
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... PYY(5697)

Description

Amino Acid Sequence

Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2

General description

Human peptide YY (PYY) is a 36 amino acid peptide secreted by mucosal L cells in the distal ileum, colon and rectum. The gene encoding PYY is localized on human chromosome 17q21.1.

Biochem/physiol Actions

Y2/Y5 Neuropeptide Y receptor agonist. Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

Hygroscopic

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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