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P2985 Sigma-Aldrich

Prostate Specific Antigen–α2-Macroglobulin Complex human

buffered aqueous solution

Synonym: PSA-A2M

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Description

Biochem/physiol Actions

Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with chymotrypsin-like enzymatic activity. Circulating PSA exists in free and protease inhibitor-bound forms. Studying the ratios of free to inhibitor-bound forms may prove valuable in the diagnosis of prostate cancer.

Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with chymotrypsin-like enzymatic activity.

Other Notes

PSA from human seminal fluid; α2-M from human plasma.

Physical form

Solution in 20 mM sodium phosphate, pH 7.4, 150 mM sodium chloride, and 0.05% sodium azide.

Safety & Documentation

Safety Information

WGK Germany 
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Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

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P3338 Prostate Specific Antigen from human semen, buffered aqueous solution

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