• USA Home
  • P3032 - Penicillin G sodium salt

EMAIL THIS PAGE TO A FRIEND
P3032 Sigma-Aldrich

Penicillin G sodium salt

powder, BioReagent, suitable for cell culture

Synonym: Benzylpenicillin sodium salt

  • CAS Number 69-57-8

  • Empirical Formula (Hill Notation) C16H17N2NaO4S

  • Molecular Weight 356.37

  •  Beilstein Registry Number 3834217

  •  EC Number 200-710-2

  •  MDL number MFCD00069666

  •  eCl@ss 34010400

  •  PubChem Substance ID 24898384

Purchase

Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Mechanism of Action,
InChI Key   FCPVYOBCFFNJFS-LQDWTQKMSA-M
product line   BioReagent
form   powder
potency   ≥1477 units per mg
application(s)   cell culture | mammalian: suitable
solubility   H2O: 100 mg/mL (Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days.)
suitability   suitable for cell culture
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-positive bacteria

Description

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Caution

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

General description

Chemical structure: ß-lactam

Other Notes

1mu,10mu,25mu,100mu

Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin Keep in a dry place.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH9800000

Documents

Certificate of Analysis

Certificate of Origin


Request a Serum Sample

Cell Culture Guide
Protocols & Articles

Articles

Inhibition of Cell Wall Biosynthesis by Antibiotics

Antibiotics are molecules that specifically target and kill cells. The term antibiotic is frequently used interchangeably with the word antibacterial, but antiviral, antifungal and antineoplastic com...
BioFiles 2006, 1.4, 7.
Keywords: Antibiotics, Antifungals, Antivirals, Building blocks, Glycosylations, Metabolism

Related Content

Antibiotics Selection Guide

The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?