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P3326 Sigma

Platelet-Derived Growth Factor-AB human

PDGF-AB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym: PDGF-AB



Analysis Note

The biological activity is measured by its ability to stimulate 3H-thymidine incorporation in quiescent NR6R-3T3 fibroblasts.

Biochem/physiol Actions

Cellular actions of platelet-derived growth factor (PDGF) include chemoattraction and activation of neutrophils, monocytes, and fibroblasts. PDGF appears to play a crucial role in the cellular response to tissue injury and is critically involved in the pathological progression of atherosclerosis.

Other Notes

Heterodimer of the A and B chains of PDGF disulfide linked.

Physical form

Lyophilized from a 0.2 μm filtered solution in 40% acetonitrile and 0.1% trifluoroacetic acid.

Price and Availability

Request a Serum Sample

Milli-Q® Water Purification Solutions
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Cellular Derived Blood Proteins and Enzymes

Cell damage is induced by reactive oxygen species (ROS). ROS are either free radicals, reactive anions containing oxygen atoms, or molecules containing oxygen atoms that can either produce free radic...
BioFiles 2006, 1.5, 4.
Keywords: Aerobic, Alzheimer Disease, Bacterial conjugations, Biofiles, Cancer, Metabolism, Oxidations, Parkinson Disease, Reductions, Respiration

Platelet Derived Growth Factors (PDGF)

Platelet-Derived Growth Factor is the principal mitogen found in mammalian serum and is released from platelets during clot formation.1 PDGF elicits multifunctional actions with a variety of cells, i...
Jennifer Fries
BioFiles 2009, 4.5, 20.
Keywords: Atomic absorption spectroscopy, Growth factors, Purification, Type

Peer-Reviewed Papers


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