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P3496 Sigma-Aldrich

(+/-)-8-Prenylnaringenin

Plant-derived estrogen receptor ligand

  • Empirical Formula (Hill Notation) C20H20O5

  • Molecular Weight 340.37

  •  MDL number MFCD00272175

  •  PubChem Substance ID 329820176

  •  NACRES NA.56

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Properties

storage temp.   −20°C
SMILES string   C\C(C)=C\Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)cc3
InChI   1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3
InChI key   LPEPZZAVFJPLNZ-UHFFFAOYSA-N

Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

8-Prenylnaringenin, a strong plant-derived estrogen receptor ligand, is a phytoestrogen that inhibits multidrug resistance-associated transporters, P-glycoprotein and MRP1. 8-Prenylnaringenin also inhibits EGF signaling at the level of phosphatidylinositol-3-OH kinase ((PI(3)K))activity.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P3496.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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