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P3662 Sigma-Aldrich

Sodium pyruvate

Hybri-Max, powder, suitable for hybridoma

Synonym: α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

  • CAS Number 113-24-6

  • Linear Formula CH3COCOONa

  • Molecular Weight 110.04

  •  Beilstein/REAXYS Number 3568341

  •  EC Number 204-024-4

  •  MDL number MFCD00002586

  •  PubChem Substance ID 24898440

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Properties

Related Categories Cell Culture, Conditioned media supplements and reagents, Hybridoma Media Supplements, Hybridoma Platform, Hybridoma Reagents,
grade   Hybri-Max
InChI Key   DAEPDZWVDSPTHF-UHFFFAOYSA-M
assay   ≥99%
form   powder
impurities   endotoxin, tested
mp   >300 °C (lit.)
solubility   H2O: 100 mg/mL
suitability   suitable for hybridoma
storage temp.   2-8°C

Description

Application

Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Packaging

25, 100 g in poly bottle

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Peer-Reviewed Papers
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References

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