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P4533 Sigma-Aldrich

Calpain II from rabbit skeletal muscle

lyophilized powder, 15-40 units/mg protein

Synonym: Calcium Activated Neutral Protease

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Description

Biochem/physiol Actions

Calpain undergoes translocation between cell compartments during the various steps of the cell cycle. It is among the proteases implicated in apoptosis and the proteasome-ubiquitine pathway of protein degradation.

Other Notes

80K subunit of mCANP

Unit Definition

One unit will produce a ΔA280 of 0.5 in 30 min at pH 7.5 at 30 °C, measured as TCA soluble products using N,N-dimethylated casein as substrate. (Final volume = 1.8 mL, light path = 1 cm.) (Modified from Kawashima, S., et al.)

Physical form

Lyophilized powder containing lactose, dithiothreitol and tris buffer salts.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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