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P5069 Sigma-Aldrich

Prostaglandin F tris salt

synthetic, cell culture tested

Synonym: (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF−Tris

  • CAS Number 38562-01-5

  • Empirical Formula (Hill Notation) C20H34O5 · C4H11NO3

  • Molecular Weight 475.62

  •  Beilstein/REAXYS Number 4087514

  •  EC Number 254-002-3

  •  MDL number MFCD00077863

  •  PubChem Substance ID 24898587

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Properties

Related Categories Allium sativum (Garlic), Biochemicals and Reagents, Cell Biology, Cell Culture, Eicosanoids (Prostaglandins, Leukotrienes),
biological source   synthetic
InChI Key   IYGXEHDCSOYNKY-RZHHZEQLSA-N
assay   ≥99%
suitability   cell culture tested
storage temp.   −20°C

Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UK8025000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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