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P5607 Sigma-Aldrich

L-Proline

from non-animal source, meets EP, USP testing specifications, suitable for cell culture

Synonym: (S)-Pyrrolidine-2-carboxylic acid

  • CAS Number 147-85-3

  • Empirical Formula (Hill Notation) C5H9NO2

  • Molecular Weight 115.13

  •  Beilstein/REAXYS Number 80810

  •  EC Number 205-702-2

  •  MDL number MFCD00064318

  •  eCl@ss 32160406

  •  PubChem Substance ID 24898677

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Properties

Related Categories Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Amino Acids, Amino Acids & Vitamins,
Quality Level   200
biological source   non-animal source
assay   98.5-101.0% dry basis
form   powder
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, tested
color   white
mp   228 °C (dec.) (lit.)
solubility   H2O: 50 mg/mL
suitability   meets EP, USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
SMILES string   OC(=O)[C@@H]1CCCN1
InChI   1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChI key   ONIBWKKTOPOVIA-BYPYZUCNSA-N

Description

Application

L-proline has been used as a component of high-glucose-Dulbecco′s modified Eagle′s medium (HG-DMEM) for chondrocyte differentiation and for the culture of chondrocyte-like cells. It has also been used as a component of yeast nitrogen base for yeast cultures.

Packaging

1 kg in poly bottle

25 kg in poly drum

25, 100 g in poly bottle

Biochem/physiol Actions

Proline is a cyclic, non-essential, hydrophobic amino acid. It is a proteinogenic amino acid which is crucial for primary metabolism. In peptide chains, proline residues confer structural constraints and enhance the susceptibility of proximal peptide bonds to protease activity.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
TW3584000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND

Pipette Controller from Brand
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

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Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

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