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P5818 Sigma-Aldrich

Protein C, Activated, Fragment 390-404 human

~90% (HPLC)

  • Empirical Formula (Hill Notation) C91H130N22O23

  • Molecular Weight 1900.14

  •  MDL number MFCD00214128

  •  PubChem Substance ID 24898709

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Other Peptides, Peptides and Proteins,
assay   ~90% (HPLC)
composition   Peptide content, ≥70%
storage temp.   −20°C
SMILES string   CCC(C)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(NC(=O)CNC(=O)C(N)Cc5ccc(O)cc5)C(C)C)C(C)O)C(C)C)C(=O)NC(Cc6cnc[nH]6)C(O)=O
InChI   1S/C91H130N22O23/c1-10-49(8)75(88(133)108-69(90(135)136)39-55-42-96-45-100-55)112-84(129)67(38-54-41-98-61-17-12-11-16-59(54)61)105-82(127)68(40-72(120)121)106-80(125)64(34-46(2)3)103-81(126)65(36-52-22-28-57(117)29-23-52)104-78(123)63(19-15-33-97-91(94)95)101-85(130)70(44-114)109-87(132)74(48(6)7)111-79(124)62(18-13-14-32-92)102-89(134)76(50(9)115)113-83(128)66(37-53-24-30-58(118)31-25-53)107-86(131)73(47(4)5)110-71(119)43-99-77(122)60(93)35-51-20-26-56(116)27-21-51/h11-12,16-17,20-31,41-42,45-50,60,62-70,73-76,98,114-118H,10,13-15,18-19,32-40,43-44,92-93H2,1-9H3,(H,96,100)(H,99,122)(H,101,130)(H,102,134)(H,103,126)(H,104,123)(H,105,127)(H,106,125)(H,107,131)(H,108,133)(H,109,132)(H,110,119)(H,111,124)(H,112,129)(H,113,128)(H,120,121)(H,135,136)(H4,94,95,97)
InChI key   ZWIJLOHGIXGMAB-UHFFFAOYSA-N
Gene Information   human ... PROC(5624)

Description

Amino Acid Sequence

Tyr-Gly-Val-Tyr-Thr-Lys-Val-Ser-Arg-Tyr-Leu-Asp-Trp-Ile-His

Biochem/physiol Actions

Fragment of activated protein C (APC) heavy chain that is essential for anticoagulant activity.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Anticoagulants

Pulmonary arterial hypertension (PAH) is characterized as a progressive, incurable disease and its treatment remains elusive.1 The mean survival rate is often less than 4 years and the median surviva...
Sami Barghshoon
BioFiles v7 n5, 2012, 25–26
Keywords: Anticoagulants, Cardiovascular, PAGE

Peer-Reviewed Papers
15

References

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