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  • PLA0235 - Rabbit anti-ERK1 Antibody, Affinity Purified

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PLA0235 Sigma-Aldrich

Rabbit anti-ERK1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym: ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, MAP kinase 3, MAP kinase isoform p44, MAPK 1, MAPK 3, PRKM3, extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, insulin-stimulated MAP2 kinase, microtubule-associated protein 2 kinase, p44-ERK1, p44-MAPK, p44erk1, p44mapk

  •  NACRES NA.41

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Properties

Related Categories Antibodies, Antibodies for Proximity Ligation Assays, Individual Antibodies More...
biological source   rabbit
application(s)   immunohistochemistry: 1:100-1:500
  immunoprecipitation (IP): 2- 5 μg/mg
  western blot: 1:2,000- 1:10,000
species reactivity   human
shipped in   wet ice
storage temp.   2-8°C
antibody form   affinity purified immunoglobulin
Quality Level   100
antibody product type   primary antibodies
grade   Powered by Bethyl Laboratories, Inc.
accession no.   NP_002737.2
Gene Information   rabbit ... ERK1(5595)

Description

Immunogen

The epitope recognized by PLA0235 maps to a region between residue 329 and 379 of human extracellular signal-related kinase 1 (mitogen-activated protein kinase 3) using the numbering given in entry NP_002737.2 (GeneID 5595).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Other Notes

Extracellular signal-regulated kinase 1 (ERK1/p44) is also known as mitogen-activated protein kinase 3 (MAPK3). ERK1 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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