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  • PLA0283 - Rabbit anti-TSG101 Antibody, Affinity Purified

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PLA0283 Sigma-Aldrich

Rabbit anti-TSG101 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym: ESCRT-I complex subunit TSG101, TSG10, VPS23, tumor susceptibility gene 101, tumor susceptibility gene 10, tumor susceptibility protein

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Properties

Related Categories Antibodies, Antibodies for Proximity Ligation Assays, Individual Antibodies More...
species reactivity   human, mouse
application(s)   western blot: 1:2,000-1:10,000
antibody form   affinity purified immunoglobulin
grade   Powered by Bethyl Laboratories, Inc.
shipped in   wet ice
storage temp.   2-8°C
Gene Information   rabbit ... TSG101(7251)
biological source   rabbit
antibody product type   primary antibodies
accession no.   NP_006283.1
UniProt accession no.   Q99816

Description

Immunogen

The epitope recognized by PLA0283 maps to a region between residue 300 and 350 of human Tumor Susceptibility Gene 101 using the numbering given in entry NP_006283.1 (GeneID 7251).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Application

Product PLA0283, Powered by Bethyl Laboratories, has been pre-qualified for use in proximity ligation assay (PLA®). PLA® technology enables visualization of protein interactions in fixed cells and tissue samples while under endogenous protein expression levels.

Other Notes

Tumor susceptibility gene 101 protein (TSG101) is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. TSG101 mediates the association between the ESCRT-0 and ESCRT-I complex. TSG101 binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). TSG101, along with CEP55, is required for completion of cytokinesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99816].

Legal Information

PLA is a registered trademark of Sigma-Aldrich Co. LLC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  nwg
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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