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ProteoPrep® Immunoaffinity Albumin & IgG Depletion Kit



Related Categories Molecular Biology, Native Protein Sample Preparation, Protein Depletion, Proteomics
storage temp.   2-8°C


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Features and Benefits

• High Capacity removes more interfering abundant proteins
• High Specifity ensures you see an accurate and more complete proteome
• Buffer systems are compatible with 2 dimensional electrophoresis so there are no intermediate time consuming steps that might result in protein loss

General description

The ProteoPrep Immunoaffinity medium in the prepacked spin columns is a mixture of two-beaded media containing recombinantly expressed, small single-chain antibody ligands, resulting in low non-specific binding and high capacity.This kit is also effective in depleting albumin and IgG from mouse and guinea pig serum.


The ProteoPrep® Immunoaffinity Albumin and IgG Depletion Kit has been designed to specifically remove albumin and IgG from human serum (25-50μL) in preparation of samples for proteomics analysis, two-dimensional electrophoresis (2DE) or liquid chromatography (LC).

Legal Information

ProteoPrep is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Ultrafree Centrifugal Filter Units
Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
My protein samples contain urea.  Can I still use the ProteoPrep® Immunoaffinity Albumin & IgG Depletion Kit, Product PROTIA, for depletion?
The presence of urea can reduce the depletion of albumin with PROTIA.  We would suggest a buffer exchange prior to depletion using either dialysis or 5 KDa NMWL cut-off spin filters.
Can I use the ProteoPrep® Immunoaffinity Albumin & IgG Depletion Kit, Product PROTIA, on samples besides serum?
Besides human serum or plasma samples, we have not specifically tested other human biological fluids with this kit.  However, in principle, there is no reason not to try the kit with other fluid samples.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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