PZ0110 Sigma-Aldrich


≥98% (HPLC)

Synonym: N-Methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl β-alanine hydrochloride, SC-57461 hydrochloride

  • CAS Number 423169-68-0

  • Empirical Formula (Hill Notation) C20H25NO3 · HCl

  • Molecular Weight 363.88

  •  MDL number MFCD00951253

  •  PubChem Substance ID 329823702

  •  NACRES NA.77



Related Categories Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
mfr. no.   Pfizer®
color   white to off-white
solubility   DMSO: >5 mg/mL
originator   Pfizer
storage temp.   2-8°C
SMILES string   Cl.CN(CCCOc1ccc(Cc2ccccc2)cc1)CCC(O)=O
InChI   1S/C20H25NO3.ClH/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17;/h2-4,6-11H,5,12-16H2,1H3,(H,22,23);1H



5, 25 mg in glass bottle

Biochem/physiol Actions

SC-57461A is an inhibitor of leukotriene A4 hydrolase.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.

Other Notes

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Pfizer is a registered trademark of Pfizer, Inc.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Discover Bioactive Small Molecules for Lipid Signaling Research

Within mammalian cells, a multitude of lipid compounds are found with a variety of cellular functions, including structural components of cell membranes and as second messengers in cell signaling pat...
Keywords: Absorption, Atomic absorption spectroscopy, Cancer, Cardiovascular, Cell signaling, Diabetes, Digestions, Diseases, Growth factors, Hormones, Inflammation, Lipid Metabolism, Lipid signaling, Metabolism

Leukotriene Receptors

Leukotrienes (LTs) exist as two distinct classes, hydroxyacids (such as LTB4), and cysteinyl leukotrienes (such as LTC4, LTD4 and LTE4). Leukotriene receptors have been classified into BLT and CysLT ...
Keywords: Addition reactions, Anti-inflammatory agents, Atomic absorption spectroscopy, Clinical, Diseases, Gene expression, Inflammation, Transduction

Pfizer Compounds for Lipid Signaling

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Lipid Signaling

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