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PZ0115 Sigma-Aldrich

CP-31398 dihydrochloride hydrate

≥98% (HPLC)

Synonym: N′-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate

  • Empirical Formula (Hill Notation) C22H26N4O·2HCl · xH2O

  • Molecular Weight 435.39 (anhydrous basis)

  •  MDL number MFCD17215956

  •  PubChem Substance ID 329823707

  •  NACRES NA.77



Related Categories Apoptosis Inducers, Apoptosis and Cell Cycle, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   100
assay   ≥98% (HPLC)
mfr. no.   Pfizer®
storage condition   desiccated
color   yellow
solubility   H2O: ≥20 mg/mL
originator   Pfizer
storage temp.   2-8°C
SMILES string   O.Cl.Cl.COc1ccc(cc1)\C=C\c2nc(NCCCN(C)C)c3ccccc3n2
InChI   1S/C22H26N4O.2ClH.H2O/c1-26(2)16-6-15-23-22-19-7-4-5-8-20(19)24-21(25-22)14-11-17-9-12-18(27-3)13-10-17;;;/h4-5,7-14H,6,15-16H2,1-3H3,(H,23,24,25);2*1H;1H2/b14-11+;;;
Gene Information   human ... TP53(7157)
mouse ... TP53(22059)
rat ... TP53(24842)



5, 25 mg in glass bottle

Biochem/physiol Actions

CP-31398 dihyrochloride hydrate is a p53 stabilizer; apoptosis inducer.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.

Other Notes

This compound was developed by Pfizer for Apoptosis & Cell Cycle research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Pfizer is a registered trademark of Pfizer, Inc.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Discover Bioactive Small Molecules for Apoptosis

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Pfizer Compounds for Apoptosis & Cell Cycle

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Apoptosis & Cell Cycle

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