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PZ0136 Sigma-Aldrich

CP-100263 dihydrochloride hydrate

≥97% (HPLC)

Synonym: (-)-CP 99994 dihydrochloride hydrate, (2R,3R)-N-[(2-Methoxyphenyl)methyl]-2-phenyl-3-piperidinamine dihydrochloride hydrate

  • Empirical Formula (Hill Notation) C19H24N2O·2HCl

  • Molecular Weight 369.33

  •  MDL number MFCD18632542

  •  PubChem Substance ID 329823721

  •  NACRES NA.77

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, CI-CZ,
Quality Level   100
assay   ≥97% (HPLC)
form   solid
mfr. no.   Pfizer®
color   white to off-white
solubility   H2O: ≥5 mg/mL
originator   Pfizer
storage temp.   room temp
SMILES string   O.Cl.Cl.COc1ccccc1CN[C@@H]2CCCN[C@@H]2c3ccccc3
InChI   1S/C19H24N2O.2ClH.H2O/c1-22-18-12-6-5-10-16(18)14-21-17-11-7-13-20-19(17)15-8-3-2-4-9-15;;;/h2-6,8-10,12,17,19-21H,7,11,13-14H2,1H3;2*1H;1H2/t17-,19-;;;/m1.../s1
InChI key   KBQMYQWHOPCSMG-ONBPXQNSSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CP-100263 is an NK-1 neurokinin receptor antagonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®Pfizer), a collection of 90 Pfizer-developed drugs and research tools. Click here to learn more.

Other Notes

This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Pfizer is a registered trademark of Pfizer, Inc.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Pfizer Compounds for Neuroscience

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Neuroscience

Tachykinin Receptors

The tachykinins represent a large family of peptides whose common structural feature is the C-terminal amino acid sequence Phe-X-Gly-Leu-Met-NH2. Substance P (SP), neurokinin A (NKA), neurokinin B (N...
Keywords: Atomic absorption spectroscopy, Clinical, Diseases, Gastrointestinal, Gene expression, Inflammation, Neurotransmission, Schizophrenia, Transduction

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