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PZ0232 Sigma-Aldrich

PF-04471141 hydrochloride

≥98% (HPLC)

Synonym: 4-(3-Pentylamino)-6,7,8-trimethoxyquinazoline hydrochloride

  • Empirical Formula (Hill Notation) C16H23N3O3 · xHCl

  • Molecular Weight 305.37 (free base basis)

  •  PubChem Substance ID 329823783

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 20 mg/mL, clear
originator   Pfizer
storage temp.   −20°C
SMILES string   CCC(CC)NC1=NC=NC2=C(OC)C(OC)=C(OC)C=C21.Cl
InChI   1S/C16H23N3O3.ClH/c1-6-10(7-2)19-16-11-8-12(20-3)14(21-4)15(22-5)13(11)17-9-18-16;/h8-10H,6-7H2,1-5H3,(H,17,18,19);1H
InChI key   QRHFQSUUJMOIHO-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

PF-04471141 is a potent, selective inhibitor of the calcium-activated phosphodiesterase PDE1. (PDE1B IC50 = 35 nM).

Other Notes

This compound was developed by Pfizer for Cyclic Nucleotides research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Pfizer Compounds for Cyclic Nucleotides

From our library of Articles, Sigma-Aldrich presents Pfizer Compounds for Cyclic Nucleotides

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