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PZ0337 Sigma-Aldrich

UK-432097

≥98% (HPLC)

Synonym: 6-(2,2-Diphenylethylamino)-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-N-(2-(3-(1-(pyridin-2-yl)piperidin-4-yl)ureido)ethyl)-9H-purine2-carboxamide

  • CAS Number 380221-63-6

  • Empirical Formula (Hill Notation) C40H47N11O6

  • Molecular Weight 777.87

  •  MDL number MFCD28137759

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, U
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
shipped in   wet ice
storage temp.   −20°C
SMILES string   O[C@@H]1[C@@H](C(NCC)=O)O[C@@H](N2C=NC(C2=N3)=C(NCC(C4=CC=CC=C4)C5=CC=CC=C5)N=C3C(NCCNC(NC(CC6)CCN6C7=CC=CC=N7)=O)=O)[C@@H]1O

Description

Biochem/physiol Actions

UK-432097 is a selective adenosine receptor A2AAR full agonist with EC50 of 0.66 ± 0.19 nM. It was recently used to map the structure of the active state of the adenosine A2A receptor.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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