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Q0125 Sigma

Quercetin dihydrate

≥98% (HPLC), powder

Synonym: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate

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Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


Milli-Q® Water Purification Solutions

Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
LK8950000

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
What is Product Q0125, Quercetin dihydrate, soluble in?
This product is soluble in DMSO (24 mg/mL). Per Merck Index 12th ed., entry #8216, 1 g of quercetin dissolves in 290 mL absolute ethanol or 23 ml hot ethanol. It is soluble in glacial acetic acid and alkaline aqueous solutions but it is practically insoluble in water.
What is the solution stability of Product Q0125, Quercetin dihydrate?
We have no data on solution stability. It is best to store solutions protected from air, the colder the better to minimize oxidation.
What is the shelf life of Product Q0125, Quercetin dihydrate?
This product does not have an assigned shelf life or expiration date.  So the standard Sigma-Aldrich guarantee of one year from date of receipt applies.
Is Product Q0125, Quercetin dihydrate,synthetic?
An initial amino acid used in the product is from plant source (Rutin); the final product is chemically synthesized.
Where would you recommend that we store Product Q0125, Quercetin dihydrate?
Powdered quercetin dihydrate should be stored at ambient temperature, in a cool dry place. Refrigeration is not necessary.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

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Peer-Reviewed Papers
15

References

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Q4951 Quercetin, ≥95% (HPLC), solid

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